Introduction: In Malaysia, the childhood vaccination program is an important preventative strategy for infectious diseases provided for free for all children under the age of 17 years old. Parental vaccine acceptance is known to be influenced by personal factors such as knowledge, attitude, beliefs, and trust toward healthcare providers (HCPs). This study aimed to examine the influence of personal factors on vaccination acceptance behaviour among parents. Methods: This cross-sectional study involved the distribution of a self-administered questionnaire among parents in a healthcare education institution. Results: A total of 251 completed questionnaires were received. Less than half (n=114, 46%) of the respondents had a high level of knowledge about children’s vaccination. Furthermore, over one-third of the parents showed negative attitudes about vaccination (n=93, 37.5%). A moderately significant positive relationship (p < 0.001) was observed between personal factors (M = 3.82, SD = .40) and vaccination acceptance (M = 4.50, SD = .53). Conclusion: Overall, respondents showed relatively positive personal factors toward vaccination in children. However, negative attitudes towards vaccination among parents must be tackled by implementing effective strategies to instil correct perception and increase vaccine acceptance in parents.
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