Rapid urbanization and aging residential areas present critical challenges to sustainable urban development in China. This study investigates the efficacy of urban acupuncture—a design strategy inspired by traditional Chinese medicine—in addressing these issues through precise, small-scale interventions. Focusing on the Nanchang Cigarette Factory Residential Area, a mixed-method approach combining descriptive statistics and stepwise multiple regression analysis was employed to evaluate data from 200 structured surveys. The findings reveal four transformative strategies: Adjusting Organ Function, Activating Acupoint Spaces, Unblocking the Meridian System, and Injecting Cultural Blood. These strategies improve infrastructure, enhance spatial layouts, and incorporate cultural heritage to revitalize neglected urban areas. This research offers a practical framework for revitalizing aging neighborhoods and promoting sustainable urban renewal. This study provides practical insights for policymakers and urban planners to enhance urban vitality and resilience.
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