This study aimed to evaluate the effect of office automation on organizational excellence in Zahedan University of Medical Sciences. Descriptive-survey has been used in this research. Research population includes 212 employees in studied case and sample size was estimated 135 persons. The data collection tool was a researcher-made questionnaire with 50 questions which had two columns of before and after applying office automation. Its validity was in content type and the reliability confirmed by Cronbach's alpha coefficient of 0.84 in SPSS software. Results show that using office automation has great effect on organizational excellence in "leadership", "strategy", and "partnership and resources". Also, the use of office automation has had great effect on organizational excellence in "people", "process, products, and services", "customer results", "people results", "society results", and "key performance results". Generally, the use of office automation has affected organizational excellence. Results also show that there is a significant difference between before and after the application of office automation. According to results, office automation had the greatest effect on "key performance results"; then, "people results" and "strategy" are on the second and third rank, respectively.
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